Table 1.

Number of preserved and lost IHCs and OHCs of different rows (OHC1, OHC2, OHC3) in CEP-1347-treated and control (CON) cochleas

Cochlea #OHCs totalLost hair cellsOHC loss total (%)
IHCOHC1OHC2OHC3
CEP-020768971402738105  (1.5)
CEP-1407669924203847105  (1.6)
CEP-060567489384558141  (2.1)
CEP-2203666617415054145  (2.2)
CEP-2003658519533764154  (2.3)
CEP-1604657328426774183  (2.8)
CEP-2503684614615376190  (2.8)
CEP-030766727726263197  (3.0)
CEP-070763876747456204  (3.2)
CEP-0305679524576093210  (3.1)
CEP-2603672317646680210  (3.1)
CEP-1101624025969161289  (4.7)
CEP-0512645425180198229607  (9.4)
CON-2007d668723959295282  (4.2)
CON-06016423265149114328  (5.1)
CON-030764213377109178364  (5.7)
CON-1903d64807789136141366  (5.6)
CON-2007s663043125111139375  (5.7)
CON-1204689756102139184425  (6.2)
CON-1903s669056118119225462  (6.9)
CON-2703650777205117184506  (7.8)
CON-04056621796156255507  (7.7)
CON-18076621796156255507  (7.7)
CON-0412684911161209281659  (9.5)
CON-0604688278156222341719  (10.4)
CON-040766901172224135141149  (17.2)
  • Guinea pigs were exposed to 120 dB, 4 kHz noise for 6 hr. Hair cell counts were done 2 weeks after the exposure.