Table 3.

Expression of Kv4.2W362F increases input resistance and the number of adapting SCG neurons 3-a

PhenotypeRin(GΩ)Vm (mV)APThresh(pA)APA (mV)APD50 (msec)APD90(msec)n
All cells68  ± 0.08−49  ± 128  ± 290  ± 23.54  ± 0.275.59  ± 0.2225
Phasic0.64  ± 0.143-150−47  ± 230  ± 73-16082  ± 33.63  ± 0.446.07  ± 0.336
Adapting0.76  ± 0.12−47  ± 126  ± 389  ± 23.47  ± 0.145.76  ± 0.2313
Tonic0.60  ± 0.093-160−53  ± 327  ± 23-15099  ± 42.90  ± 0.094.90  ± 0.203-2136
  • F3-150 ,

  • F3-160 Values are significantly different from those in wild-type cells at the p < 0.003* and p < 0.001** levels.

  • F3-213 Values are significantly different from those in phasic or adapting cells at the p < 0.01 level.

  • F3-a All values are means ± SEM.