Table 1.

Distribution patterns of Eph receptors and ephrins within parasagittal domains of Purkinje cells during the middle period of cerebellar development

Zone/lobulesEphA4Ephrin-A5EphA3Ephrin-A2
Posterior IXA (lower), B, DAbsentHomogeneous-EGLA (higher), B, D
Figs. 4, 7,9Fig. 4Figs. 4, 8Figs. 4, 7
VIII1-aA (Lm–Hl), B, DC, EHomogeneous-EGLA (Hm–Ll), B, D
Figs. 4, 7, 9Fig.4, 6Figs. 4, 8Figs. 4G, 7D
Central VI, VIIM, A (lateral), B (Hm–Lc–Hl), DA1-b (medial), C, EA (medial), B, D (low)M, A (medial), B (Lm–Hc–Hl), D
Figs. 4,6, 7, 9Figs. 4C, 6CFigs. 4, 8Figs. 4, 7
Anterior I–VM, A (lateral), B (medial), DA (medial), B (lateral), CAbsent (stops at lobule V)M, A (lateral), B (medial)
Figs. 4, 6, 7Figs. 4, 6Fig. 4Figs. 4,7
  • Gradients within bands are described only if relevant to the localization of late born cells or the expression of a cognate ligand. M refers to the thin zone bordering the midline in band A (Fig.4B, midline asterisk). EGL, external granule layer; Hm, high medial, Hl, high lateral, Lc, low central, Lm, low medial, Ll, low lateral.

  • F1-a Except for the expression of ephrin-A5, this lobule would be classified as a posterior lobule because the expression pattern of the other molecules is similar to that of lobule IX.

  • F1-b The expression of ephrin-A5 in band A of lobule VII is uncertain.