Table 3.

Characteristics of quantal events from control and VMAT2-transfected PC12 cells

Molecules releasedFoot moleculesimax(pA)t1/2(msec)ispike (msec)
Control73,500  ± 55007400  ± 5009.29  ± 0.532.53  ± 0.10321  ± 33
VMAT2283,400  ± 36,90012,300  ± 80017.53  ± 1.403.25  ± 0.11253  ± 31
VMAT/Control (%)385%3-165167%188%3-165129%3-16579%
  • Indicated are the mean ± SEM values of quantal size (Molecules released), number of molecules released during foot events (Foot molecules), maximal amplitude (imax), width at half height (t1/2), and interspike interval (ispike) and the number of events recorded per stimulation. The % difference (VMAT/control values) between the categories is also noted. The control group represents 346 events from 9 cells and the VMAT2 group consists of 349 events from 11 cells.

  • F3-165 p < 0.001, Kolmogorov–Smirnov statistics.