Table 4.

Characteristics of quantal events recorded from control and VMAT2-transfected VTA neurons from sister cultures recorded over a 24 hr period

Molecules releasedimax(pA)t1/2(μsec)ispike (msec)
Control7400  ± 7007.96  ± 0.51270  ± 231645  ± 321
VMAT219,300  ± 80012.42  ± 0.24816  ± 50630  ± 57
VMAT/Control (%)261%4-165156%4-165302%4-16538%4-165
  • Indicated are the mean ± SEM values of quantal size (Molecules released), maximal amplitude (imax), width at half height (t1/2), and mean interspike interval (ispike). The % difference (VMAT2/control values) between the categories is noted. The control group represents 88 events from eight exposures to α-latrotoxin, and the VMAT2 group consists of 975 events from nine exposures.

  • F4-165 p < 0.001, Kolmogorov–Smirnov statistics.