Table 1.

Ba2+ currents in cultured mouse neurons

KOWild type
Total current364.9  ± 50.4375.8  ± 47.6
Nimodipine36.1  ± 8.244.7  ± 8.4
ω-Aga IVA75.0  ± 15.0105.3  ± 15.6
ω-CTx GVIA139.2  ± 30.795.4  ± 22.1
SNX-4821.8  ± 1.345.5  ± 6.9
Resistant112.8  ± 26.884.9  ± 20.54
  • Comparison of the peak IBa (pA) from cultured mouse cerebellar granule cells (α1E knock-out,n = 5; wild type, n = 9). Data represent peak current amplitudes (pA) blocked by the specific toxin or drug indicated and the remaining resistant current. Data are given as mean ± SEM.