Table 2.

Unbiased stereological analysis

Monkey numberDensity of THVolumeTH cell countNon-TH countAll neurons
30 d OVX without estrogen
30 d OVX with 30 d estrogen treatment
  • The total number of all neurons, that of TH-immunoreactive cells, their density, and the volume of the compact zone of the substantia nigra unilaterally in different experimental groups are shown.

  • Unbiased stereological analysis of two key groups showed small but significant differences in the total volume of the pars compacta and significant differences between the groups for TH density, total TH cell count, and total number of neurons. There was no significant difference between the groups for the count of non-TH cells.