Table 1.

Voltage dependence of fast-gating transitions1-a

ActivationInactivation
V1/2 (mV)k(mV)nV1/2(mV)k (mV)n
WT−27.0 ± 2.58.0 ± 0.28−70.9 ± 1.64.7 ± 0.18
R669H−24.5 ± 0.87.2 ± 0.316−72.5 ± 0.24.7 ± 0.211
  • F1-a The differences in the mean values were not different from 0 (p > 0.05) for any of the estimated gating parameters.