Table 1.

Effect of long-term nicotine treatment on the temporal pattern of egg-laying

Animal type (number, hours, intervals)Intracluster time constant (1/λ1; sec)Intercluster time constant (1/pλ2; sec)pλ1 (sec−1)λ2 (sec−1× 10−3)
N2 (naive) (8, 46, 237)18  ± 21240  ± 1600.545  ± 0.0350.057  ± 0.0081.5  ± 0.22
Nicotine-adapted N2 (t = 0 hr) (6, 33, 50)5  ± 238401-160  ± 10800.380  ± 0.0820.203  ± 0.1520.7  ± 0.25
Nicotine-adapted N2 (t = 24 hr) (5, 30, 105)11  ± 220401-160  ± 10800.490  ± 0.0530.095  ± 0.0211.0  ± 0.22
unc-29(x29) (3, 19, 78)11  ± 219801-160  ± 4800.673  ± 0.0500.090  ± 0.0150.75  ± 0.38
  • F1-160 The intercluster intervals (>300 sec in duration) were significantly longer than those in wild type as determined by the Mann-Whitney rank-sum test (p < 0.05). See Materials and Methods for parameter estimation and SD calculation.