Table 1.

GFAP immunoreactivity in dorsal striatum

TreatmentTotal number of astrocytes% of control number astrocytesTotal number of clusters% of control number of clusters
Saline11  ± 2.2100  ± 18.53  ± 0.8100  ± 45.1
Paraquat (10 mg/kg)20  ± 5.4169  ± 464  ± 0.88130  ± 26.5
Maneb (30 mg/kg)19  ± 4.3161  ± 36.55  ± 0.62140  ± 18.4
Paraquat + maneb44  ± 11*373  ± 98.2*9  ± 1.4*,,1-159275  ± 42*,,1-159
  • Numbers of reactive astrocytes 1 (n = 6), PQ (10 mg/kg; n = 6), MB (30 mg/kg; n = 6), and PQ + MB (n = 5) groups. Bonferroni–Dunnpost hoc analysis indicates significant differences from either control paraquat alone or maneb alone.

  • Significantly different:

  • * , from control;

  • , from paraquat alone;

  • F1-159 , from maneb alone.