GABAergic and non-GABAergic cells' mean average discharge rate (PSH), instantaneous firing frequency (ISIH), rhythmic discharge rate (ACH), unit-to-EEG cross-correlation frequency (STA), and associated dominant EEG spectral peak during prestimulation and stimulation conditions 3-a
| Group percent | Unit rate (PSH, Hz) | Unit frequency (ISIH, Hz) | Unit rhythmic frequency (ACH, Hz) | Unit-to-EEG frequency (STA, Hz) | EEG spectral peak (Hz) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Prestimulation | Stimulation | Prestimulation | Stimulation | Prestimulation | Stimulation | Prestimulation | Stimulation | Prestimulation | Stimulation | ||
| Nb+/GAD+ cells average† | 100% | 17.91 ± 2.78 (20) | 17.31 ± 3.84 (20) | 60.52 ± 27.69 (20) | 60.62 ± 26.99 (20) | 1.42 ± 0.39 (4) | 1.52 ± 0.14 (5) | 1.08 ± 0.21 (9) | 1.69 ± 0.14 (3) | 0.97 ± 0.13 (16) | 3.20 ± 0.21 (16)3-165 |
| high: 29.34 ± 3.05 (7) | high: 31.81 ± 3.74 (7) | ||||||||||
| “On” average § | 40% | 23.15 ± 5.22 (8) | 33.01 ± 5.61 (8)3-160 | 28.49 ± 6.32 (8) | 49.29 ± 14.63 (8) | 0.86 (1) | — | 0.68 ± 0.01 (3) | — | 1.16 ± 0.21 (8) | 3.21 ± 0.25 (8)3-165 |
| On (tonic) | high: 30.88 ± 5.31 (4) | high: 31.81 ± 3.74 (7) | |||||||||
| “Off” average | 60% | 14.40 ± 2.82 (12) | 6.85 ± 2.03 (12)3-165 | 81.88 ± 45.67 (12) | 68.17 ± 44.64 (12) | 1.61 ± 0.49 (3) | 1.52 ± 0.14 (5) | 1.28 ± 0.29 (6) | 1.69 ± 0.14 (3) | 0.77 ± 0.12 (8) | 3.19 ± 0.36 (8)3-165 |
| high: 27.30 ± 2.22 (3) | |||||||||||
| Off (tonic-cluster) | 25% | 18.90 ± 3.00 (5) | 9.18 ± 3.07 (5)3-160 | 26.32 ± 4.26 (5) | 37.78 ± 6.22 (5) | 1.5 (1) | 1.52 ± 0.14 (5) | 1.49 ± 0.01 (2) | 1.69 ± 0.14 (3) | 0.55 ± 0.05 (2) | 3.66 ± 0.74 (2) |
| high: 27.30 ± 2.22 (3) | |||||||||||
| Off (burst) | 20% | 16.88 ± 5.73 (4) | 8.30 ± 4.23 (4) | 208.6 ± 121.73 (4) | 155.00 ± 133.77 (4) | 0.82 (1) | — | 0.82 ± 0.01 (2) | — | 1.11 ± 0.13 (3) | 3.26 ± 0.52 (3) |
| Off (tonic) | 15% | 3.62 ± 0.75 (3) | 0.99 ± 0.51 (3) | 5.53 ± 1.60 (3) | 3.02 ± 0.68 (3) | 2.5 (1) | — | 1.53 ± 0.98 (2) | — | 0.61 ± 0.16 (3) | 2.80 ± 0.79 (3) |
| Nb+/GAD− cells average | 100% | 8.95 ± 1.51 (34)†† | 12.93 ± 1.84 (34)3-165(†) | 25.17 ± 5.12 (34) | 31.27 ± 8.38 (34) | 1.40 ± 0.28 (10) | 2.02 ± 0.26 (15) | 1.01 ± 0.30 (12) | 2.34 ± 0.31 (15)3-150 | 1.24 ± 0.13 (26) | 2.71 ± 0.18 (26)3-165 |
| high: 23.82 ± 3.57 (6) | high: 33.28 ± 4.92 (5) | ||||||||||
| “On” average | 82% | 8.98 ± 1.58 (28)§§§ | 14.76 ± 1.96 (28)3-165§§§(§) | 26.09 ± 6.00 (28) | 35.85 ± 9.93 (28) | 1.40 ± 0.28 (10) | 2.06 ± 0.28 (14) | 0.71 ± 0.80 (10) | 2.17 ± 0.28 (14)3-150 | 1.14 ± 0.09 (21) | 2.63 ± 0.20 (21)3-165 |
| high: 23.82 ± 3.57 (6) | high: 33.28 ± 4.92 (5) | ||||||||||
| On (tonic) | 35% | 12.10 ± 2.77 (12) | 20.72 ± 3.19 (12)3-165(§) | 26.51 ± 5.34 (12) | 29.90 ± 4.08 (12) | 0.84 ± 0.14 (3) | — | 0.79 ± 0.12 (4) | 2.10 ± 1.42 (2) | 1.30 ± 0.17 (10) | 2.72 ± 0.31 (10)3-165 |
| high: 23.70 ± 0.70 (3) | high: 24.70 ± 5.03 (2) | ||||||||||
| On (cluster) | 29% | 7.57 ± 2.50 (10) | 10.28 ± 2.45 (10)3-160 | 19.32 ± 4.25 (10) | 21.67 ± 4.02 (10) | 1.41 ± 0.30 (4) | 1.62 ± 0.13 (10) | 0.78 ± 0.14 (3) | 1.57 ± 0.12 (7) | 1.14 ± 0.15 (5) | 2.60 ± 0.27 (5)3-150 |
| high: 23.93 ± 7.95 (3) | high: 39.00 ± 5.51 (3) | ||||||||||
| On (burst) | 18% | 5.06 ± 1.61 (6) | 10.3 ± 2.74 (6)3-150 | 40.33 ± 7.67 (6) | 71.37 ± 45.06 (6) | 1.95 ± 0.83 (3) | 3.15 ± 0.71 (4) | 0.55 ± 0.16 (3) | 3.02 ± 0.44 (5)3-150 | 0.91 ± 0.06 (6) | 2.86 ± 0.39 (6)3-160 |
| “Off” average | 18% | 8.81 ± 4.78 (6) | 4.39 ± 3.50 (6)3-150 | 17.10 ± 7.68 (6) | 9.92 ± 5.51 (6)3-150 | — | 1.55 (1) | 2.50 ± 1.71 (2) | 4.73 (1) | 1.61 ± 0.60 (5) | 3.01 ± 0.46 (5)3-150 |
| Off (tonic) | |||||||||||
↵F3-a Mean ± SEM (withn in parentheses) values are presented for the prestimulation and stimulation conditions for Nb+/GAD+ and Nb+/GAD− cell groups and subgroups. Within each group or subgroup, measures were compared across the prestimulation and stimulation conditions by pairedt tests for the unit discharge PSH and ISIH values and for the EEG spectral peak or by unpaired t tests for ACH and STA values (
↵F3-150 p < 0.05;
↵F3-160 p < 0.01;
↵F3-165 p< 0.001). GAD− groups or subgroups were compared with homologous GAD+ cell groups or subgroups by ANOVA, and a significant difference indicated by the specific symbol of the GAD+ group (shown in the first column) with which the comparison was made (with one symbol =p < 0.05, two symbols = p < 0.01, or three symbols = p < 0.001). Symbols in parentheses indicate that the GAD− cell group differed from the GAD+ cell group according to a two-way ANOVA with group (GAD− or GAD+) as a between factor and condition (prestimulation and stimulation) as repeated measure within each group. Symbols out of parentheses indicate that they differed according to a one-way ANOVA between groups in the prestimulation or stimulation condition.