Table 1.

Cardiovascular variables in rats reared at 18°C and 30°C and changes evoked by acute hypothermia and disinhibition of raphe pallidus neurons

Rearing temperatureControlAcute hypothermiaBIC in RPa
MAP (mmHg)PP (mmHg)HR (bpm)ΔMAP (mmHg)ΔPP (mmHg)ΔHR (bpm)ΔMAP (mmHg)ΔPP (mmHg)ΔHR (bpm)
18°C108  ± 459  ± 2345  ± 8+11  ± 3+9  ± 2+41  ± 7+18  ± 3+12  ± 2*+70  ± 7
30°C106  ± 457  ± 4357  ± 7+11  ± 4+14  ± 3+55  ± 9+22  ± 4+23  ± 5+84  ± 14
  • MAP, Mean arterial pressure; PP, pulse pressure; HR, heart rate; Δ, evoked change;BIC, bicuculline; RPa, raphe pallidus.

  • * Significant difference (p < 0.05) between 18°C- and 30°C-reared rats.