Table 2.

Serial section analysis of synaptic immunogold labelling for NMDARs

Rat 1Rat 2Rat 3
No. of Analyzed synapses2-a255273225
No. of particles per synapse2-b7.920  ± 5.526.075  ± 4.0610.06  ± 6.45
Range of particles per synapse0–350–241–31
% of Immunonegative synapses1.570.370
No. of Synapses for area measurement2-c226240201
Synaptic area (μm2)2-b0.040  ± 0.0230.040  ± 0.0230.046  ± 0.024
Particle density (No./μm2)b,d206.68  ± 122.4171.54  ± 103.8224.34  ± 113.3

  • ↵F2-a All synapses included, irrespective of the plane of the section relative to the synaptic cleft.

  • ↵F2-b Mean ± SD.

  • ↵F2-c PSD area measured only for synapses sectioned at an angle revealing at least some of the synaptic cleft.

  • F2-d Density = number of particles in a synapse/synaptic area.