Table 3.

Physiologic values for experiment 8 (mouse focal ischemia–intravenous MnTE-2-PyP5+ after treatment)

Vehicle (n = 15)MnTE-2-PyP5+ 1 mg (n = 17)MnTE-2-PyP5+ 2 mg (n = 18)
Preischemia body weight (gm)22  ± 122  ± 123  ± 1
Day 1 body weight (gm)21  ± 121  ± 121  ± 1
10 min before ischemia
 MAP (mmHg)78  ± 580  ± 578  ± 6
 Arterial pH7.19  ± 0.067.20  ± 0.047.19  ± 0.04
 PaCO2 (mmHg)37  ± 336  ± 337  ± 3
 PaO2 (mmHg)189  ± 27183  ± 30176  ± 28
 Pericranial temperature (°C)37.0  ± 0.137.0  ± 0.137.0  ± 0.1
25 min after onset of ischemia
 MAP (mmHg)74  ± 676  ± 575  ± 6
 Pericranial temperature (°C)37.0  ± 0.137.0  ± 0.237.0  ± 0.1
10 min after termination of ischemia
 MAP (mmHg)71  ± 572  ± 573  ± 5
 Pericranial temperature (°C)37.0  ± 0.137.0  ± 0.137.0  ± 0.1
  • All values are mean ± SD. MAP, Mean arterial pressure; PaCO2, arterial carbon dioxide partial pressure; PaO2, arterial oxygen partial pressure. There were no differences among groups.