Table 3.

IC50 values for [3H]spiperone binding

LigandIC50m)
Spiperone0.11  ± 0.03
Haloperidol0.31  ± 0.15
L 7458703.06  ± 1.21
U 1019587.66  ± 3.33
PD 16807726.10  ± 3.12
Apomorphine5.96  ± 2.15
Apocodeine6.41  ± 1.49
Dopamine77.82  ± 10.10
  • IC50 values were calculated from each displacement curve. The results are presented as the mean ± SE of three to five independent experiments.