Table 2.

GABAA currents are comparable in ORAs and VRAs

ORAVRAORA/VRA
GABA (1 mm)
 AP(pA)−829 ± 259 (n = 6)−1092 ± 359 (n = 5)0.76
 CD (pA/pF)107.8 ± 19.7 (n = 6)32.4 ± 2.2 (n = 5)3.3
 Ad/AP(%)56.5 ± 4.869.3 ± 10
Muscimol (50 μm)
 AP(pA)−719 ± 222 (n = 6)−840 ± 442 (n = 5)0.86
 CD (pA/pF)98.0 ± 33.4 (n = 6)21.6 ± 7.0 (n = 5)4.5
Bicuculline (10 μm)
 % of inhibition of GABA (1 mm)-induced current58 ± 10 (n = 6)69 ± 8 (n = 5)
  • Values are in mean ± SEM with cell numbers in parentheses. AP and Ad are peak and current amplitudes at the end of GABA pulses, respectively. CD, Current density calculated for capacitance differences. None of the apparent differences between ORAs and VRAs were significant by Student's t test.