Table 2.

Effects of Kv1.5W461F and Kv4.2W362F expression on SCG neuron firing properties^{^2-a}

		R_in(GΩ)	V_m (mV)	AP_Thresh(pA)	APA (mV)	APD₅₀ (msec)	APD₉₀(msec)	n
Wild type	All cells	0.34 ± 0.03	−48 ± 1	46 ± 5	82 ± 4	3.66 ± 0.14	5.92 ± 0.20	28
	Phasic	0.26 ± 0.02	−45 ± 2	67 ± 1	80 ± 5	4.18 ± 0.24	6.55 ± 0.34	12
	Adapting	0.60 ± 0.06	−48 ± 1	24 ± 2	87 ± 3	3.57 ± 0.20	5.96 ± 0.20	9
	Tonic	0.22 ± 0.02	−52 ± 1	42 ± 2	91 ± 3	2.97 ± 0.03	4.87 ± 0.20	7
Kv1.5W461F	All cells	0.38 ± 0.04	−48 ± 1	32 ± 3	89 ± 8	3.08 ± 0.14	5.26 ± 0.25	25
	Phasic	0.30 ± 0.03	−49 ± 2	43 ± 6^2-160	90 ± 3^*	3.16 ± 0.18^*	5.36 ± 0.37^*	6
	Adapting	0.48 ± 0.06	−47 ± 2	24 ± 2	89 ± 3	3.25 ± 0.24	5.51 ± 0.45	11
	Tonic	0.30 ± 0.05	−50 ± 1	36 ± 5	92 ± 2	2.77 ± 0.21	4.84 ± 0.41	8
Kv4.2W362F	All cells	0.68 ± 0.08	−49 ± 1	28 ± 2	90 ± 2	3.54 ± 0.27	5.59 ± 0.22	25
	Phasic	0.64 ± 0.14^2-160	−47 ± 2	30 ± 7^2-160	82 ± 3	3.63 ± 0.44	6.07 ± 0.33	6
	Adapting	0.76 ± 0.12	−47 ± 1	26 ± 3	89 ± 2	3.47 ± 0.14	5.76 ± 0.23	13
	Tonic	0.60 ± 0.09^2-160	−53 ± 3	27 ± 2^2-160	99 ± 4	2.90 ± 0.09	4.90 ± 0.20	6
Kv1.5W461F + Kv4.2W362F	All cells	1.08 ± 0.17^2-160	−44 ± 2	35 ± 4	88 ± 3	3.07 ± 0.19^*	5.11 ± 0.30^*	38
	Phasic	0.36 ± 0.04^*	−43 ± 4	38 ± 7^2-160	90 ± 7	2.76 ± 0.24^2-160	4.71 ± 0.31^2-160	5
	Adapting	1.28 ± 0.17^*	−42 ± 2	25 ± 2	81 ± 6	3.75 ± 0.43	6.11 ± 0.66	17
	Tonic	0.47 ± 0.04^2-160	−47 ± 2	31 ± 5	94 ± 4	2.65 ± 0.24	4.54 ± 0.39	16

↵F2-a All values are means ± SEM. R_in, Input resistance;V_m, resting membrane potential; AP_thresh, current required to reach the threshold for generating an action potential; APA, action potential amplitude.
Mean values are significantly different from those in wild-type cells at the
↵* p < 0.03 and
↵F2-160 p < 0.005 levels.