Table 2.

Effect of cannabinoid agonists WIN55,212-2 (1 μm, marked with a) and CP55,940 (1 μm, marked with b) on the amplitude of eIPSC recorded in rat BLA and CA or in the basolateral complex of wild-type (CB1+/+) mice and knock-out (CB1−/−) mice

eIPSCnspeciesControlAmplitude (pA) CB1 agonistEffect %
BLA6Rat475.1  ± 60305.8  ± 66a61.1  ± 6*
BLA7Rat408.8  ± 66235.7  ± 35b59.4  ± 6*
CA5Rat337.4  ± 30357.8  ± 37a105.7  ± 3
CB1+/+5Mouse865.5  ± 91487.1  ± 81a56.3  ± 4*
CB1−/−5Mouse610.5  ± 41635.2  ± 49a104.0  ± 3
  • All data are presented as mean ± SEM. Significant values (p < 0.05) are bold and marked with an asterisk.n indicates the number of recorded cells in a given experiment.