Table 1.

Behaviors observed during microdialysis sample collection in the 10 min periods during and after BLA stimulation

BehaviorsControlsLY354740LY293558
DuringAfterDuringAfterDuringAfter
Ambulation63013*033
Grooming059025011*
Freezing9656948110056
Sniffing48636*502256
Mouth movement63268169*100*67*
Jaw tremor4833313878*89*
  • Data are presented as percentages of animals that exhibited selected behaviors within each group. The control group (n = 27) had normal Ringer's perfused into the microdialysis probe implanted in the PFC. In the other two groups, either the mGluR2 agonist LY354740 (n = 16) or the AMPA/kainate antagonist LY293558 (n = 9) was added to the Ringer's solution that was perfused into the PFC. All animals were at rest for the 10 min period before BLA stimulation (data not shown). Asterisks denote significant differences (p < 0.05) compared with the control group.