ACh-elicited current waveform parameters in DA neurons of WT and α4 −/− mice
| WT (n = 8) | α4 −/− (n = 15) | |
|---|---|---|
| Amplitude | 132 ± 26 pA | 72 ± 7 pA4-160 |
| Rise time | 242 ± 38 msec | 96 ± 17 msec4-160 |
| Decay T1/2 | 562 ± 66 msec | 316 ± 47 msec4-160 |
Decay T1/2 was the time measured between peak and half maximal amplitude.
↵F4-160 p < 0.01.