Table 1.

Summary of functional properties of unitary IPSCs generated at the BC–BC synapse

Mean ± SEM[Range] (n)
Unitary IPSCs1-a
 Latency IPSC1-b0.8  ± 0.05 msec[0.6–1.2] (14)
 20–80% rise time of IPSC1-b0.3  ± 0.02 msec[0.2–0.46] (14)
 Decay τw of IPSC1-b,1-c2.5  ± 0.2 msec[1.1–3.8] (14)
 Decay τ11-b,1-c1.6  ± 0.1 msec[1.0–2.0] (11)
 Decay τ21-b,1-c11.0  ± 2.3 msec[3.7–26.7] (11)
 Ampl. contr. fast comp.1-b,1-c76.8  ± 7.8%[21–99] (11)
 Peak amplitude IPSC1-b,1-d110  ± 19 pA[34–234] (14)
 Percentage of failures10  ± 5%[0–48] (14)
Paired-pulse depression1-e
 PPD at 10 msec32  ± 4.6%[15–52] (17)
 Recovery from PPD, τ0.63 sec(17)
Multiple-pulse depression (50 Hz)1-e
 Onset τ1 (ampl. contr.)0.025 sec (42%)(3)
 Onset τ2 (ampl. contr.)5.1 sec (37%)(3)
Block of IPSCs1-e
 20 μmbicuculline94  ± 1%[92–97] (4)
Inferred postsynaptic conductance change1-a
 Rise τ0.17  ± 0.04 msec[0.09–0.2] (3)
 Decay τ1.8  ± 0.6 msec[1.0–2.9] (3)
 Peak amplitude (all sites)1-f7.6  ± 4.2 nS[1.9–15.8] (3)
  • F1-a  Data from rigorously identified BC–BC pairs.

  • F1-b  Values were determined from average IPSCs.

  • F1-c  Based on visual criteria, a biexponential fit was judged to be superior in 11 pairs (yielding time constant values τ1, τ2, and an amplitude-weighted decay time constant τw), whereas a monoexponential fit was adequate in the remaining 3 pairs (yielding a time constant τm). The overall value given is the mean of τw and τm values.

  • F1-d  Including failures.

  • F1-e  Data from both rigorously and tentatively identified BC–BC pairs.

  • F1-f  With the surface area of the somatodendritic domain of the reconstructed BCs (mean 12082 μm2), this would correspond to a mean conductance density of 0.063 mS/cm2.