Number of motoneurons in z-specific agrin mutant mice (agrinΔz/Δz) and their wild-type and heterozygous (control) littermates
| Control | AgrinΔz/Δz | % increase | |
|---|---|---|---|
| Trochlear | 171 ± 11 (7) | 259 ± 13 (5)2-165 | 51 |
| Trigeminal motor | 1180 ± 50 (6) | 1380 ± 64 (6)* | 17 |
| Facial | 4530 ± 178 (6) | 4964 ± 169 (5) | 10 |
| Hypoglossal | 1964 ± 164 (2)2-a | 2518 (1) | 28 |
Control and agrinΔz/Δz values are the average ± SEM. The values in parentheses indicate the number of animals examined (
↵* p < 0.05,
↵F2-165 p < 0.001). Percentages (%) refer to the increase in the number of motoneurons with respect to the controls.
↵F2-a The control values were 1800 and 2128 hypoglossal motoneurons.