Table 1.

Quantitation of Congo Red birefringent neurons in Tg mice

CA1CA2CA3
Tg214 (11 month)22.5 ± 18.7%77.0 ± 5.0%37.5 ± 9.1%
Non-Tg littermate (11 month)NDNDND
  • Percentage of total neurons in hippocampal subregions that were Congo Red-positive. Total number of neurons and Congo Red birefringent neurons were counted in each region under light microscopy with or without polarizing filter. Counting was performed using three different mice, and data were expressed as mean ± SD. ND, None detected.