Table 1.

Summary of brain structures assayed for circadian rhythmicity in Per1-luc bioluminescence

Rhythmic areas% Rhythmic (n)Damp rate (cycles)Phase (hr)Arrhythmic areasn
SCN100  (42)>109.7  ± 0.5Au12
Pin100  (10)1.3  ± 0.421.2  ± 0.2BNSTp3
Pit100  (16)2.9  ± 0.314.3  ± 0.8CE3
RCH100  (4)1.8  ± 0.111.7  ± 0.1CP5
ME100  (2)1.3  ± 0.311.5  ± 1.8DR6
OB100  (6)1.6  ± 0.411.5  ± 0.3HI13
AN95  (19)1.7  ± 0.214.3  ± 0.7M1p3
PVN92  (12)1.0  ± 0.017.1  ± 0.6MR3
LH75  (4)0.8  ± 0.314.4  ± 3.4MS7
VOLT50  (8)0.8  ± 0.517.3  ± 2.3NA6
VLPO43  (7)1.1  ± 0.518.7  ± 1.8PC10
PVT40  (5)1.0  ± 0.022.4  ± 5.6S18
SON38  (8)0.4  ± 0.213.0  ± 3.1SN7
VTA4
  • Cultures that showed at least two peaks with a near 24 hr period were defined as rhythmic (see Materials and Methods). The numbers of explants studied are indicated in parentheses. Damping rate is the number of circadian cycles that exceeded 30% of the magnitude of the first cycle (mean ± SEM; see Materials and Methods), and phase is the time of the first circadian peak relative to the animal's previous light cycle in which dawn and dusk occurred at 0 and 12 hr, respectively.