Age | % Ipsilaterala | dLGN areab (mm2) | dLGN length along the dorsoventral axisc(μm) | Location of ipsilateral geometric centerd (μm) |
---|---|---|---|---|
P8 | ||||
WT (n = 7) | 16.0 ± 1.9 | 0.150 ± 0.01 | 637.6 ± 39.2 | 68.0 ± 27.9 |
β2−/− (n = 9) | 23.9 ± 7.8* | 0.134 ± 0.02 | 552.5 ± 54.4 | 108.6 ± 24.0 |
P14 | ||||
WT (n = 6) | 12.0 ± 2.4 | 0.245 ± 0.02 | 811.7 ± 52.9 | 93.4 ± 13.0 |
β2−/− (n = 6) | 18.5 ± 5.9* | 0.203 ± 0.02 | 707.0 ± 59.4* | 162.3 ± 17.9* |
P28 | ||||
WT (n = 4) | 16.1 ± 2.0 | 0.262 ± 0.02 | 839.3 ± 49.4 | 69.9 ± 43.1 |
β2−/− (n = 4) | 28.1 ± 5.7* | 0.266 ± 0.04 | 821.8 ± 27.9 | 135.7 ± 14.4* |
Mean values for the middle third of the dLGN (± SD) are shown.
↵* Significant differences from age-matched wild-type mice (Student's t test; p < 0.05). % Ipsilateral (a) corresponds to the total area of the ipsilateral projection normalized to the total area of the dLGN (b). The length of the dLGN (c) is measured from the dorsal pole to the center of the ventral edge. The location of the geometric center of the ipsilateral projection (d) along the dorsoventral axis was measured relative to the geometric center of the dLGN. Positive numbers correspond to a dorsal displacement. WT, Wild type.