Table 2.

Effects of chronic MPEP treatment on premature performance after 6-OHDA lesion

MPEP (mg/kg)PrePostFirst weekSecond weekThird week
028  ± 3.228  ± 3.228  ± 3.127  ± 2.529  ± 2.4
1.528  ± 4.030  ± 5.037  ± 4.035  ± 6.034  ± 5.0
327  ± 2.529  ± 3.641  ± 3.52-a,2-b41  ± 2.62-a,2-b44  ± 1.62-a,2-b
626  ± 3.029  ± 3.039  ± 4.02-a,2-b38  ± 4.02-a,2-b33  ± 3.0
  • Values correspond to the mean number of premature responses ± SEM per six sessions during the various blocks of the experiment. The first block (pre) represents the six sessions preceding the surgery, the second (post) corresponds to the six sessions after lesion, the three others correspond to the 3 weeks of MPEP treatment (first, second, and third weeks).

  • F2-a Significant difference from preoperative performance (p < 0.05 pairedt test after significant ANOVA).

  • F2-b Significant difference from postoperative performance (p < 0.05 pairedt test after significant ANOVA).