Table 2.

Changes in hippocampal gene expression between mice expressing low levels of CaMKII–Asp286

Accession numberGene nameFold change
NM_013697.1Transthyretin33.1
M64086.1spi2 proteinase inhibitor (spi2/eb4)24.9
AB005141.1Klotho23.8
U52925Coagulation factor V9.6
AI845874Unknown6.3
AI847646Unknown5.6
NM_008489.1Lipopolysaccharide-binding protein4.1
L14811.1Prolactin receptor3.7
NM_015744.1Ectonucleotide pyrophosphatase/ phosphodiesterase 22.3
AJ222814.1B-cell-specific protein2.1
AW049647Unknown2.1
M13227.1Enkephalin−2.4
X13986.1Minopontin−5.7
  • Hippocampal RNA was screened on Affymetrix gene chips (Mouse U74). Compensatory changes in gene expression in three mice with low levels of CaMKII–Asp286 (one mouse with the transgene on during development, two mice with the transgene off during development) compared with the same two wild-type mice used for Table 1. Genes that were scored as changed over twofold in at least four of the six possible comparisons between transgenic and control mice are shown.