Table 2.

Quantification of facial motor neurons and lateral deep cerebellar nucleus neurons

Age and genotypeNeuron numberNucleus volume (mm3)
Facial motor neurons
 P1+/+5676  ± 1110.079224  ± 0.0026
−/−4021  ± 1062-a0.064719  ± 0.00212-b
 P14+/+4960  ± 2660.123  ± 0.0058
−/−3662  ± 1092-c0.115  ± 0.00672-d
(−26%)
Lateral (dentate) deep cerebellar neurons (relative number at one level)
 P14+/+362  ± 23
−/−243  ± 262-e
(−33%)
  • Values represent the mean ± SEM. (%) represents cell loss relative to p73+/+. p values were obtained using Student's t test.

  • F2-a p < 0.001;

  • F2-b p < 0.05;

  • F2-c p < 0.01;

  • F2-d p < 0.05;

  • F2-e p < 0.05;n = 3 in all cases.