Table 3.

Contribution of Kv2.1- and Kv2.2-encodedI_K to action potential repolarization^a

	Peak current density	Current density at APD₅₀	Current density at APD₉₀	n
HEK-293 Tf Kv2.1
Phasic	27 ± 3	21 ± 2	10 ± 3	10
Adapting	38 ± 3	33 ± 3	14 ± 3
Tonic	39 ± 4	32 ± 4	16 ± 3
HEK-293 Tf Kv2.2
Phasic	23 ± 3	18 ± 3	9 ± 2	11
Adapting	28 ± 4	23 ± 5	12 ± 3
Tonic	33 ± 4	27 ± 5	12 ± 3
SCG wild type
Phasic	52 ± 2	38 ± 1	10 ± 1	21
Adapting	60 ± 3	46 ± 2	10 ± 1
Tonic	59 ± 3	50 ± 3	11 ± 1
SCG Tf Kv2.1DN
Phasic	30 ± 2**	22 ± 1**	7 ± 1**	18
Adapting	42 ± 1**	33 ± 2**	10 ± 1
Tonic	42 ± 2**	35 ± 2**	7 ± 1*
SCG Tf Kv2.2DN
Phasic	35 ± 2**	24 ± 1**	6 ± 1**	17
Adapting	44 ± 2**	33 ± 2**	9 ± 1
Tonic	43 ± 3**	34 ± 2**	6 ± 1*

F3-a All values (in picoamperes per picoFarad) are means ± SEM of data obtained from cells stimulated with an average phasic, adapting, or tonic action potential waveform.
*^,**Mean values are significantly different from those in wild-type SCG cells at the *p < 0.01 and **p < 0.002 levels.