Table 1.

Cerebellar area, Purkinje, and granule cell numbers in wild-type, mutant control (scm/scm), and fivescm/scm ↔ BALB/cJ chimeras

AnimalsCoat color (%)cb area1-a (μm2)Total PCs1-bE-PCs1-bTotal GCs1-c
Wild type05,675,7336000 (0.0%)150,266
Chimera 144,790,40047127 (5.6%)87,073
Chimera 285,451,20046135 (7.5%)90,343
Chimera 3203,905,60038358 (15.0%)65,762
Chimera 4603,961,067502174 (34.7%)75,608
Chimera 5981,974,400395249 (63.1%)24,624
scm/scm1001,411,200327310 (95.0%)14,168
  • cb, Cerebella; PCs, Purkinje cells; E-PCs, ectopic Purkinje cells; GCs, granule cells.

  • F1-a Cerebellar areas (cb area) are means of three sections that are at a distance of 150 μm from each other in the medial cerebellum.

  • F1-b Total Purkinje cells (PCs) and ectopic Purkinje cells (E-PCs) are means of four sections in the medial cerebellum. In parentheses are the percentages of total Purkinje cells that are ectopic.

  • F1-c Total granule cell numbers are means of two sections at a distance of 150 μm from each other in the medial cerebellum.