Corticocortical, corticothalamic, and intra-thalamic relationships in rat H16
| Leading site | Lagging site | First 500 msec | Whole seizure | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Association (%) | Time delay (msec) | Association (%) | Time delay (msec) | |||||||
| Mean | Mean | Range | n | Mean | Mean | Range | n | |||
| A | Cx − focus | → Cx − HP | 56.2 | 2.9 | 1.5–5.5 | 10 | 54.2 | 4.9 | 4.0–6.5 | 9 |
| B | Th − VPM | → Cx − focus | 0 | 38.7 | 18.4 | 15.5–20.0 | 7 | |||
| Cx − focus | → Th − VPM | 41.0 | 8.1 | 7.0–10.0 | 8 | 26.1 | 8.8 | 8.5–9.0 | 2 | |
| B | Th − VPL | → Cx − HP | 23.4 | 30.0 | 1 | 28.6 | 29.3 | 24.0–32.5 | 6 | |
| Cx − HP | → Th − VPL | 30.5 | 11.7 | 7.5–15.5 | 3 | 0 | ||||
| C | Th − VPL | → Th − VPM | 69.1 | 4.3 | 3.0–6.5 | 10 | 80.0 | 3.1 | 2.5–3.5 | 9 |
| C | Th − LD | → Th − VPM | 47.8 | 6.1 | 3.5–10.0 | 8 | 47.5 | 9.9 | 6.5–12.0 | 9 |
Summary of the corticocortical (A), corticothalamic (B), and intra-thalamic (C) interdependencies during spontaneous absence seizures (n = 10) in rat H16. The values for the strength of association (%) and time delay (msec) are given both for the first 500 msec and for the whole duration of the seizure. Direction-specific averages were made for the association parameters. For the corticocortical (A) and intra-thalamic (C) associations, the delay was always found in the same direction, and thus averages were made of all seizures for which a time delay could be established. For the corticothalamic associations, however, delays were found in both directions, and thus separate averages were made for those cases in which the thalamus was leading and for those cases in which the cortex was leading.