Table 1.

Histological properties of DRG neurons

Bladder (n = 460 cells) Proximal urethra (n = 364 cells) Distal urethra (n = 320 cells)
NF-negative C-fiber neurons 321 cells (70%) (24.1 ± 1.5 μm) 247 cells (68%) (24.5 ± 1.4 μm) 163 cells (51%a) (23.5 ± 1.5 μm)
IB4 (+) 58/321 (18%) 55/247 (22%) 80/163 (49%a)
IB4 (−) 263/321 (82%) 192/247 (78%) 83/163 (51%a)
NF-positive A-fiber neurons 139 cells (30%) (32.1 ± 1.8 μm) 117 cells (32%) (33.3 ± 1.8 μm) 157 cells (49%a) (36.8 ± 2.0 μm)b
IB4 (+) 4/137 (3%) 6/117 (5%) 5/157 (3%)
IB4 (−) 133/137 (97%) 111/117 (95%) 152/157 (97%)
  • Data were obtained from four animals (six to seven DRG sections per each animal). NF, Neurofilament.

  • a p < 0.05 compared with the percentage of bladder or proximal urethral neurons (ϰ2 test).

  • b p < 0.05 compared with the diameter of bladder or proximal urethral neurons (t test).