Table 1.

Comparison of the A.U.C. for nocifensive behaviors elicited by intraplantar formalin injection in male and female wild-type C57BL/6 mice

A.U.C.
WT C57BL/6 male mice Untreated 78.68 ± 3.139
Untreated + DLT 55.88 ± 5.060
MS-pretreated 85.75 ± 3.182
MS-pretreated + DLT 36.50 ± 5.556*
WT C57BL/6 female mice Untreated 81.58 ± 3.205
Untreated + DLT 72.16 ± 2.621
MS-pretreated 82.82 ± 2.529
MS-pretreated + DLT 52.75 ± 5.303**

  • DLT, 5 μg of Deltorphin.

  • ↵* p < 0.01 (ANOVA, Bonferroni's MCT, untreated plus DLT vs MS-pretreated plus DLT).

  • ↵** p < 0.001 (ANOVA, Bonferroni's MCT, untreated plus DLT vs MS-pretreated plus DLT).