Table 2.

Activation curve parameters for TEA-sensitive and TEA-resistant currents

Wild type medp value
Control (100 μm TEA)
V½ (mV) −8.1 ± 1.6 0.3 ± 3.5 0.06
k (mV) 10.5 ± 0.7 12.5 ± 1.4 0.23
Gmax (nS) 55 ± 5 61 ± 5 0.44
300 μm to 1 mm TEA
V½ (mV) 8.7 ± 2.1 11.4 ± 2.2 0.39
k (mV) 12.4 ± 0.6 12.7 ± 0.6 0.73
Gmax (nS) 47 ± 7 51 ± 9 0.69
1 mm TEA-resistant
V½ (mV) 8.3 ± 1.7 7.4 ± 1.9 0.73
k (mV) 11.1 ± 0.4 10.8 ± 0.3 0.57
Gmax (nS) 58 ± 6 56 ± 9 0.84
Iberiotoxin-sensitive
V½ (mV) −12 ± 3 −11 ± 3 0.70
k (mV) 6.4 ± 0.7 7.9 ± 0.9 0.19