Effect of PIP2 on gM in BFSG C-cells
| Initial IM at 30 sec (pA) | IM at 4 min (pA) | |
|---|---|---|
| ATP-free internal (n = 7) | 621.5 ± 77.3 | 519.7 ± 91.4 (n.s.) |
| ATP-free internal + PIP2 | 824.4 ± 242.2 | 721.6 ± 233.4 (n.s.) |
| (20 μm; n = 5) | (n.s. vs ATP-free) | |
| ATP-free internal (n = 9) | 817.3 ± 89.0 | 864.4 ± 92.2 (n.s.) |
| ATP-free internal + PIP2 | 734.2 ± 130.8 | 882.9 ± 162.3 (p < 0.02) |
| (100 μm; n = 11) | (n.s. vs ATP-free) |
Paired t tests were used to compare current amplitudes at 30 sec and 4 min in each cell studied. Unpaired t tests were used to compare differences between groups of cells after 4 min of recording under various experimental conditions. Whole-cell recordings were used in all cases. n.s., Not significant.