MNI Coordinates of peak activation | ||||||
---|---|---|---|---|---|---|
Brain Region | x | y | z | Z value of peak activation | p Valuee SVC | |
a, Main effect of rTMS increase (−30, −26, 62) as index region for PPIa | ||||||
Sensorimotor | Left | −38 | −20 | 46 | 3.28 | 0.07 |
Premotor (PMd) | Left | −14 | −6 | 66 | 3.59 | 0.029 |
Cingulate motor (rostral) | Left | −4 | 14 | 34 | 3.62 | 0.026 |
b, Sensorimotor (−42, −26, 56) as index region for PPIb | ||||||
Sensorimotor | Left | −38 | −20 | 46 | 3.61 | 0.028 |
c, PMd (−26, −14, 68) as index region for PPIc | ||||||
Sensorimotor | Left | −36 | −22 | 44 | 3.32 | 0.061 |
Right | 44 | −22 | 42 | 4.03 | 0.007 | |
d, SMA (−12, −4, 56) as index region for PPId | ||||||
Sensorimotor | Left | −34 | −22 | 48 | 3.69 | 0.021 |
Left | −30 | −26 | 54 | 4.04 | 0.006 |
↵ a TMS site as index area: coordinates of brain regions to which the TMS site is less sensitive after rTMS.
↵ b-d Three movement-related activations as index areas. Coordinates of brain regions showing increased coupling with left sensorimotor region (b), left dorsal premotor region (c), and left SMA after real-rTMS (d), compared with sham-rTMS.
↵ e p < 0.05 (small volume correction, using values in Table 2).