Table 1.

Morphological defects in VC neurons observed using VC::GFP transgenes

Genetic backgrounda Type of protein mutated Number of VC cell bodies per wormb Number of VC process gaps per wormb % Worms with normal VC processes at vulvab
Wild type 6.0 ± 0 0.0 93
unc-34 Transcription factor 5.2 ± 0.3 0.1 ± 0.1 67
unc-76 PKC binding protein 5.4 ± 0.2 0.3 ± 0.2 67
unc-4 Transcription factor 6.0 ± 0.1 0.4 ± 0.2 93
unc-5 Netrin receptor 5.7 ± 0.2 0.9 ± 0.2 47
unc-75 RNA-binding protein 5.3 ± 0.2 1.1 ± 0.3 40
unc-115 Actin binding protein 4.7 ± 0.3 1.1 ± 0.3 13
unc-42 Transcription factor 5.7 ± 0.2 0.7 ± 0.2 20
  • PKC, Protein kinase C.

  • a Strains are listed in increasing order of egg-laying hyperactivity.

  • b n ≥ 15 for analysis at each magnification. When indicated, errors represent SEM.