Table 1.

Changes in membrane potential, conductance, and variance with the UP state

State
Parameter In vitroIn vivo/anesthetized In vivo/natural sleep/waking
DOWN-UP transition (mV) 4-10 10-15a 9.6b
10-15c
7.6 ± 2.1 14.6 ± 4.2d
Change in Gm (nS) 4-32 23e 27b
12.8 ± 7.8 74f
UP state noise (SD) (mV) 2.0-3.5 4-5a 2-3 UP state, REM sleep and wakingb
4 ± 2c
2.43 ± 0.57 2-3g
  • Values are either range or mean ± SD according to which of these was reported. REM, Rapid eye movement.

  • a Anderson et al. (2000a).

  • b Steriade et al. (2001), their Figures 5, 8, and 9.

  • c Destexhe and Pare (1999).

  • d Stern et al. (1997).

  • e Contreras et al. (1996), their Figures 2 and 3.

  • f Paré et al. (1998), their Figure 7.

  • g Metherate and Ashe (1993), their Figures 1 and 5.