Glucose (mg/dl) | Var | Insulin (ng/ml) | Var | Temperature (°C) | Var | P-Tau | |
---|---|---|---|---|---|---|---|
Starvation | |||||||
Control | 183 ± 14 | = | 2.3 ± 1.3 | = | 37.9 ± 0.2 | = | = |
3 d.S. | 115 ± 17** | − | 0.1 ± 0.1* | − | 27.7 ± 0.9** | − | + |
3 d.S. plus glucose | 175 ± 20 | = | 0.4 ± 0.5 | − | 37.5 ± 0.2 | = | = |
Insulin | |||||||
Control | 224 ± 19 | = | 3.6 ± 0.6 | = | 36.9 ± 0.4 | = | = |
Insulin | 62 ± 4** | − | 13.9 ± 0.1** | + | 29.9 ± 1.7** | − | + |
Insulin plus glucose | 60 ± 1** | − | 13.8 ± 0.6** | + | 35.5 ± 0.9 | = | = |
Deoxyglucose | |||||||
Control | 183 ± 46 | = | 1.0 ± 0.2 | = | 36.9 ± 0.4 | = | = |
Deoxyglucose | 466 ± 5** | + | 1.3 ± 0.8 | = | 29.5 ± 0.9** | − | + |
Glucose | 200 ± 36 | = | 1.7 ± 0.3 | = | 36.5 ± 0.1 | = | = |
Var, Variations from the control condition; d.S., days starvation; =, no significant change; −, decrease; +, increase; ±, slight increase; *p < 0.05; **p < 0.01. Decreases in rectal temperature correlated with increases in tau phosphorylation for all of the treatments.