Morphometric analysis of DA neuron areas and SN volumes in CBLG-DT and WT mice
| PND 7-9 | Adult | |||||
|---|---|---|---|---|---|---|
| Genotype | n | Cell area (μm3) | SN volume (μm3 × 106) | n | Cell area (μm3) | SN volume (μm3 × 106) |
| WT | 7 | 232 ± 6.3 | 555 ± 33 | 8 | 185 ± 5.4 | 739 ± 25 |
| CBLG-DT | 7 | 370 ± 11.1* | 616 ± 26 | 8 | 191 ± 5.8 | 778 ± 37 |
At PNDs 7-9, DA neurons were significantly larger in double-transgenic mice. There was no difference in SN volume. In adult animals, there was no difference in either neuron size or SN volume.
↵* p < 0.001.