Table 2.

Quantification of relative TFL-Zn fluorescent intensities in blood vessel (major axis; 30-100 μm) walls of Znt3-/- brain (cortex or hippocampus, excluding leptomeningeal vessels), heart, liver, and kidney compared with Znt3+/+ (n = 6 in each group)

Tissue ZnT3+/+ ZnT3-/-p
Cerebral cortex 100.00 ± 0.48 79.80 ± 0.63 5.8 × 10-10
(98.73-101.86) (77.97-82.02)
Heart 100.00 ± 1.26 97.55 ± 1.20 0.19
(94.54-103.61) (94.01-100.71)
Liver 100.00 ± 2.88 97.60 ± 3.21 0.59
(93.21-111.70) (94.55-110.81)
Kidney 100.00 ± 1.23 97.58 ± 1.47 0.24
(96.05-104.04) (92.17-101.47)
  • The values are means ± SEM (range in brackets) normalized to the mean fluorescent value (in arbitrary units) for the Znt3+/+ tissue. p values are for t tests (two-tailed).