Table 1.

Functional clustering of genes restricted to or enriched in specific hippocampal subregions

Functional category Restricted Enriched Total
Signal transduction 5 13 18
Regulation of transcription 4 9 13
Ion channels/transporters 2 7 9
Cytoskeletal/structural molecules 3 5 8
Energy metabolism 0 7 7
Growth factors or growth factor-binding proteins 3 2 5
Calcium ion-binding proteins 3 1 4
Carbohydrate metabolism 3 1 4
Extracellular matrix proteoglycans 2 2 4
Proteases/protease inhibitors 2 1 3
Receptor tyrosine kinases/phosphatases 1 2 3
G-protein-coupled receptors 0 3 3
RNA-binding proteins 1 1 2
Vesicle-mediated transport 0 2 2
Secretory granule proteins 0 2 2
Endocytosis/endosomal proteins 0 2 2
Other or unknown 8 15 23