Table 1.

β-Adrenergic effects on probe trial retention performance in a water maze

	Time in training quadrant	Time in opposite quadrant	Platform crossing latency
Saline^a (n = 14)	21.7 ± 1.0^b	5.8 ± 1.1^b	8.1 ± 1.1^b
Propranolol^a
1.0 mg/kg (n = 11)	20.4 ± 1.1	5.9 ± 1.2	10.1 ± 1.7
3.0 mg/kg (n = 11)	21.1 ± 1.7	7.9 ± 2.3	8.4 ± 1.6
Xamoterol^a
3.0 mg/kg (n = 10)	21.1 ± 1.9	7.8 ± 1.0	19.9 ± 5.8^*
10.0 mg/kg (n = 9)	17.4 ± 1.8^*	9.0 ± 1.4	28.8 ± 6.6^**

^* p < 0.05; ^**p < 0.01 compared with the saline group.
↵ a Drugs were administered subcutaneously in a volume of 2.0 ml/kg 60 min before the 60 sec probe trial.
↵ b Values are expressed in seconds (mean ± SEM).