Table 1.

Comparisons of mean intensity of labeling for δ, α4, and γ2 subunits in the molecular layer of control and pilocarpine-treated mice between 1 and 60 d after status epilepticus

Intensity of labeling ±SEM Percentage of difference in pilocarpine versus control mice
Subunit Time (d) Control Pilo F value p value
δ 1 86.4 ± 2.5 85.1 ± 0.9 −1.6 0.39 n.s.
4 94.0 ± 0.7 65.1 ± 0.4 −30.7 1413.25 <0.01
7 93.0 ± 7.5 61.3 ± 2.3 −34.1 25.14 <0.05
14 95.5 ± 2.1 69.8 ± 6.1 −26.9 10.22 <0.05
30 94.9 ± 1.6 48.7 ± 4.0 −48.6 76.75 <0.01
60 81.2 ± 0.9 50.1 ± 2.5 −38.4 86.60 <0.01
α4 1 37.3 ± 3.3 30.2 ± 0.7 −19.0 14.69 <0.05
4 29.2 ± 5.6 19.1 ± 1.4 −34.6 4.97 n.s.
7 33.5 ± 4.5 26.6 ± 1.7 −20.6 2.97 n.s.
14 35.1 ± 5.4 44.8 ± 3.5 +27.5 2.54 n.s.
30 32.7 ± 0.7 44.4 ± 1.3 +35.5 41.51 <0.01
60 33.3 ± 2.3 43.1 ± 4.4 +29.7 2.77 n.s.
γ2 1 112.9 ± 3.9 108.8 ± 0.8 −3.6 1.75 n.s.
4 112.1 ± 8.5 102.9 ± 3.2 −8.2 1.49 n.s.
7 109.2 ± 7.9 126.6 ± 1.6 +15.9 7.80 n.s.
14 104.0 ± 11.1 118.8 ± 6.1 +14.3 1.69 n.s.
30 102.4 ± 2.1 120.2 ± 5.1 +17.4 6.86 n.s.
60 100.0 ± 0.3 119.2 ± 4.1 +19.2 13.18 <0.05
  • Pilo, Pilocarpine; n.s., not significant.