Name/function | Axot plus LI | Axot | Ratio | Other observations | Probe set |
---|---|---|---|---|---|
SPRR1 (axon growth, cytoskeleton)a | 6297 | 1912 | 3.3 | PNS (Bonilla et al., 2002) | 1371248_at |
C/EBP-σ (transcription)a | 26.5 | 5.5 | 4.8 | LTP (Taubenfeld et al., 2001) | 1387343_at |
Cysteine-rich protein 3/LIM | 14.3 | 8.3 | 1.8 | PNS (Tanabe et al., 2003) | 1398243_at |
SOCS-3 (cytokine signaling) | 11.5 | 1.6 | 6.9 | Survival (Raghavendra Rao et al., 2002) | 1377092_at |
Lipocalin 2 | 10.4 | 7.0 | 1.4 | 1387011_at | |
Sphingosine kinase 1 | 9.4 | 1.6 | 5.8 | Survival (Edsall et al., 1997) | 1368254_a_at |
GAP-43 (axon growth, plasticity)a | 9.3 | 2.9 | 3.2 | PNS (Benowitz and Routtenberg, 1997) | 1367930_at |
4-Hydroxyphenylpyruvic acid dioxygenase | 7.3 | 1.8 | 4.2 | 1368188_at | |
Galanin (neuropeptide) | 7.1 | 2.9 | 2.6 | PNS (Zigmond and Sun, 1997) | 1387088_at |
HSP 27 | 6.7 | 7.5 | −1.2 | PNS (Costigan et al., 2002) | 1367577_at |
Retinoic acid-binding protein 2 | 6.6 | 4.9 | 1.3 | PNS (Costigan et al., 2002) | 1370391_at |
GADD45-γ | 6.0 | 3.7 | 1.7 | PNS (Tanabe et al., 2003) | 1388792_at |
iGb3 synthase | 5.6 | 1.8 | 3.1 | PNS (Tanabe et al., 2003) | 1370561_at |
MAFK | 5.3 | 6.9 | −1.3 | PC12 (Torocsik et al., 2002) | 1372211_at |
GADD 45-α | 5.3 | 4.8 | 1.1 | PNS (Tanabe et al., 2003) | 1368947_at |
Best5 | 4.9 | 1.3 | 3.8 | 1370913_at | |
Metallothionein | 4.7 | 2.9 | 1.7 | PNS (Chung et al., 2003) | 1371237_a_at |
ATF 3 (transcription) | 4.6 | 4.1 | 1.1 | PNS (Tsujino et al., 2000) | 1369268_at |
Retinol-binding protein 1 | 4.6 | 2.0 | 2.2 | PNS (Zhelyaznik et al., 2003) | 1367939_at |
GFAP | 4.5 | 1.7 | 2.6 | PNS (Aldskogius and Kozlova, 1998) | 1368353_at |
Fn14 (FGF-regulated protein 2) | 4.5 | 5.0 | −1.2 | PNS (Tanabe et al., 2003) | 1371785_at |
ATP-binding cassette subfamily B (MDR/TAP)-1A | 4.4 | 5.7 | −1.3 | PNS (Tanabe et al., 2003) | 1370464_at |
Serine (or cysteine) proteinase inhibitor, G-1 | 4.4 | 1.7 | 2.5 | 1372254_at | |
Myxovirus (influenza virus) resistance 3 | 4.3 | 1.1 | 3.9 | 1387283_at | |
ASCT2 (Na+ -dependent amino acid transporter) | 4.3 | 2.4 | 1.8 | 1371040_at | |
Tumor-associated glycoprotein pE4 | 4.3 | 3.2 | 1.3 | PNS (Costigan et al., 2002) | 1370177_at |
Importin β-3 (karyopherin β-3 subunit) | 4.3 | 2.5 | 1.8 | 1373955_at | |
Lysozyme | 4.2 | 2.8 | 1.5 | PNS (Tanabe et al., 2003) | 1370154_at |
Anthrax toxin receptor 2 | 4.1 | 3.3 | 1.2 | 1389017_at | |
Tissue inhibitor of metalloproteinase 1 | 4.0 | 1.4 | 2.9 | Survival (La Fleur et al., 1996) | 1367712_at |
Interferon regulatory factor 7 (IRF-7) | 4.0 | 1.3 | 3.2 | 1383564_at | |
Cytochrome c oxidase, subunit Vla, polypeptide 2 | 3.9 | 5.0 | −1.3 | PNS (Tanabe et al., 2003) | 1367782_at |
Endothelin converting enzyme-like 1 | 3.9 | 4.3 | −1.1 | PNS (Nakagomi et al., 2000) | 1368923_at |
Glycoprotein (transmembrane) nmb | 3.8 | 4.8 | −1.3 | 1368187_at | |
Small cell adhesion glycoprotein (smagp) | 3.7 | 1.6 | 2.3 | 1372734_at | |
Galectin 3 | 3.7 | 6.4 | −1.8 | PNS (Costigan et al., 2002) | 1386879_at |
Heme oxygenase | 3.7 | 3.3 | 1.1 | PNS (Magnusson et al., 2000) | 1370080_at |
Moesin | 3.6 | 3.9 | −1.1 | 1371575_at | |
Syntenin | 3.6 | 3.9 | −1.1 | 1376973_at | |
Kinesin family member 22 | 3.6 | 2.6 | 1.4 | 1372516_at | |
C/EBP-β (transcription)a | 3.5 | 4.4 | −1.3 | LTP(Taubenfeld et al., 2001) | 1387087_at |
CD24 antigen | 3.5 | 3.9 | −1.1 | PNS (Shewan et al., 1995) | 1369953_a_at |
Protein tyrosine phosphatase, non-receptor, type 5 | 3.4 | 1.6 | 2.1 | PNS (Tanabe et al., 2003) | 1368421_at |
Endothelial monocyte-activating polypeptide | 3.3 | 2.2 | 1.6 | 1375170_at | |
Kidney predominant protein NCU-G1 | 3.3 | 3.4 | −1.0 | 1371946_at | |
Serine protease inhibitor | 3.2 | 1.0 | 3.1 | 1368224_at | |
CREM | 3.2 | 1.8 | 1.7 | PNS (Costigan et al., 2002) | 1369737_at |
Cell death activator CIDE-A | 3.1 | 2.4 | 1.3 | 1389179_at | |
3-Phosphoglycerate dehydrogenase | 3.0 | 3.0 | −1.0 | 1367811_at | |
fos-related antigen | 3.0 | 3.4 | −1.2 | 1373035_at | |
CTL target antigen | 3.0 | 3.4 | −1.2 | 1367838_at | |
Neurolysin (metallopeptidase M3 family) | 3.0 | 3.1 | −1.1 | PNS (Tanabe et al., 2003) | 1369669_at |
LPS-induced TNF-α factor | 3.0 | 2.2 | 1.3 | 1370928_at | |
Cholinergic receptor, nicotinic, α6 | −3.0 | −2.8 | −1.0 | 1369845_at | |
Netrin-G1a | −3.1 | −2.5 | −1.3 | 1376311_at | |
Inwardly-rectifying K+ -channel, K4 | −3.2 | −3.2 | 1.0 | PNS (Xiao et al., 2002) | 1370110_at |
Proline transporter | −3.4 | −2.0 | −1.7 | 1398457_at | |
Phosphofructokinase | −3.4 | −3.6 | 1.0 | PNS (Xiao et al., 2002) | 1386961_at |
Thyroid hormone-response protein-1 | −3.5 | −2.9 | −1.1 | 1370302_at | |
Glutamate receptor, ionotropic, 2 | −3.7 | −2.9 | −1.3 | PNS (Costigan et al., 2002) | 1387171_at |
Rab 3B protein | −3.7 | −3.4 | −1.1 | 1370061_at | |
Monoglyceride lipase | −3.7 | −4.3 | 1.1 | 1388644_at | |
Leucine-rich repeat protein 3, neuronal | −3.8 | −3.7 | −1.1 | 1368964_at | |
Thyroid hormone-responsive protein (spot14) | −3.9 | −3.3 | −1.2 | 1371400_at | |
FXYD domain-containing ion transport reg.7 | −4.2 | −7.4 | 1.8 | 1368696_at | |
Insulin-like growth factor I | −4.3 | −3.3 | −1.3 | 1388469_at | |
Rabphilin 3A | −4.3 | −5.0 | 1.2 | 1390477_at | |
Calcyon; D1 receptor-interacting protein | −5.1 | −5.5 | 1.1 | 1376345_at | |
Opsin 4 (melanopsin) | −5.4 | −4.4 | −1.3 | 1374302_at | |
Na+ -channel, voltage-gated, type 1 α polypeptide | −5.7 | −4.5 | −1.4 | PNS (Xiao et al., 2002) | 1369210_at |
Visinin-like 1 | −5.8 | −3.5 | −1.7 | PNS (Xiao et al., 2002) | 1368853_at |
Cholinergic receptor, nicotinic, α3 | −6.3 | −6.5 | 1.1 | 1369001_at | |
Neuritin | −9.2 | −5.0 | −1.8 | 1386969_at |
Axot plus LI, Ratio of hybridization signals between axotomized RGCs exposed to the effects of lens injury and normal RGCs; Axot, ratio of signals between RGCs subjected to axotomy alone versus normal controls; Ratio, ratio of signals between axotomy plus lens injury versus axotomy alone; PNS, studies on axon regeneration in the peripheral nervous system; LTP, changes in expression seen during long-term potentiation in the hippocampus.
↵ a Results based on QRT-PCR.