Table 2.

Metabolic rates (μmol · gm-1 · min-1) in the awake rat brain derived from the model (Gruetter et al., 2001) extended as in Figure 1 but without oxaloacetate-fumarate cycling

CMRglc(ox)VPDHVPCVgVNTVxVexEmbedded ImageEmbedded Image
13C only 0.91 ± 0.06 1.13 ± 0.14 0.14 ± 0.03 0.40 ± 0.09 0.57 ± 0.21 1.9 ± 1.0 0.22 ± 0.06 9.0 ± 1.4 16.5 ± 2.0
13C and 14C 0.95 ± 0.07 1.19 ± 0.15 0.17 ± 0.02 0.38 ± 0.07 0.45 ± 0.10 2.1 ± 1.1 0.16 ± 0.04 9.1 ± 1.3 17.2 ± 2.1
  • Values are given as mean ± SD. Glial and neuronal ATP synthesis rates were calculated for the condition in which all glucose phosphorylation occurs in glia (i.e., x = 0 in Eqs. 2, 3).