Table 1.

Incentive anticipation-elicited activations by subject group

Contrast Region Talairach coordinates z-value Uncorrected p
Gain versus nongain anticipation
Adults R insula 33 17 3 5.60 <0.0001
R NAcc 12 18 -3 7.044 <0.00001
L NAcc -12 16 -3 7.024 <0.00001
R medial caudate 10 8 1 7.274 <0.00001
L medial caudate -10 -1 12 5.62 <0.0001
L NAcc -11 8 -1 7.476 <0.00001
R putamen 21 10 -3 6.88 <0.00001
L midbrain -4 -27 1 5.836 <0.00001
R midbrain 8 -26 7 5.87 <0.0001
R thalamus 5 -10 12 5.950 <0.00001
L thalamus -8 -21 14 6.185 <0.00001
L thalamus -4 -22 4 6.15 <0.0001
R cuneus 1 -75 11 4.927 <0.00001
Adolescents R insula 39 11 5 4.34 <0.0001
R NAcc 11 11 -3 3.956 <0.0001
L NAcc -7 8 -2 5.746 <0.00001
R extended amygdala 8 4 -7 4.201 <0.00001
R dorsal midbrain 5 -29 -1 4.634 <0.00001
L thalamus -5 -10 10 4.14 <0.00001
L thalamus -5 -16 10 4.177 <0.0001
L dorsal caudate -16 -6 17 5.094 <0.00001
Loss versus nonloss anticipation
Adults Mesial prefrontal cortex -5 53 1 -5.05 <0.0001
R parahippocampal gyrus 27 0 -13 -3.96 <0.0001
R mesial caudate 7 10 5 4.03 <0.0001
L midbrain -5 -27 -4 4.23 <0.0001
Adolescents R mesial frontal gyrus 32 47 0 3.99 <0.0001
R insula 39 17 3 4.30 <0.0001
R mesial caudate 10 0 14 4.35 <0.0001
R tail caudate 31 -39 5 4.46 <0.0001
L tail caudate -30 -46 5 4.04 <0.0001
  • Deactivations presented in italics.