Number of growth cones | Response type (%) | ||||
---|---|---|---|---|---|
Pause | <20 μm/hr | >20 μm/hr | >40 μm/hr | ||
Anti-SCG10 mAb | 30 | 37 | 37 | 23 | 3 |
Control Ab | 33 | 0 | 3 | 73 | 24 |
The number of pauses and the elongation rates of growth cones treated with anti-SCG10 mAb were compared with that in growth cones treated with a Cy2-donkey anti-rabbit control antibody. The number of anti-SCG10 mAb-treated versus control antibody-treated growth cones in each of the four response categories was significantly different (p<0.001; Fisher exact test).