Table 4.

Effect of arcaine or spermidine administration into the amygdala on the behavior of rats in the open field test

Drug (nmol) Latency to leave the central area (sec) Number of central areas crossed Number of peripheral areas crossed
PBS (100) 1.6 ± 0.5 3.0 ± 0.5 21.3 ± 4.4
Arcaine (0.02) 1.0 ± 0.1 3.7 ± 0.9 22.4 ± 3.4
Spermidine (0.02) 1.0 ± 0.08 3.4 ± 0.9 25.3 ± 7.3
Statistical analysis F(2,23) = 1.67; p > 0.05 F(2,23) = 0.22; p > 0.05 F(2,23) = 0.14; p > 0.05
  • Data are reported as the means ± SEM for eight to nine animals in each group.