Table 1.

Results from choline uptake assays and CHT immunoblotting analyses (mean ± SEM)

Right mPFC Left mPFC Right posterior cortex Left posterior cortex Striatum
Task Vmax (pmol·mg−1·5 min−1) Km2m) LP1/LP1 + LP2 (AU) Vmax (pmol·mg−1·5 min−1) Km2m) LP1/LP1 + LP2 (AU) Vmax (pmol·mg−1·5 min−1) Km2m) LP1/LP1 + LP2 (AU) Vmax (pmol·mg−1·5 min−1) Km2m) LP1/LP1 + LP2 (AU) Vmax (pmol·mg−1·5 min−1) Km2m) LP1/LP1 + LP2 (AU)
NP 14.72 ± 0.48 0.91 ± 0.02 0.31 ± 0.03 13.36 ± 0.68 1.05 ± 0.02 0.40 ± 0.02 15.25 ± 0.25 1.16 ± 0.02 0.40 ± 0.02 13.64 ± 0.45 0.88 ± 0.05 0.43 ± 0.01 37.13 ± 2.53 0.78 ± 0.10 0.42 ± 0.03
SRTT 19.43 ± 1.07 1.03 ± 0.04 0.43 ± 0.01 16.15 ± 1.32 1.16 ± 0.06 0.33 ± 0.01 16.04 ± 1.00 1.18 ± 0.05 0.36 ± 0.02 14.25 ± 0.54 1.12 ± 0.06 0.42 ± 0.02 28.11 ± 1.74 1.19 ± 0.03 0.37 ± 0.03
CVT 23.58 ± 0.58* 1.12 ± 0.03 0.50 ± 0.03* 15.52 ± 0.65 1.05 ± 0.03 0.34 ± 0.02 17.07 ± 0.92 0.83 ± 0.04 0.40 ± 0.02 13.73 ± 0.57 1.11 ± 0.03 0.46 ± 0.02 38.75 ± 1.91 0.96 ± 0.04 0.46 ± 0.03
  • AU, Arbitrary units.

  • * Significantly different from NP data, based on Tukey's honestly significant difference (p < 0.05).